Newsletter No. 03/15 - 19/08/2015

Center for Male Reproduction
Newsletter 03/15
Dear colleagues,
We are delighted to share with you our recent research

Authors: Esteves SC, Gosálvez J, López-Fernández C, Núñez-Calonge R, Caballero P, Agarwal A, Fernández JL
Int Urol Nephrol. 2015 Jul 31. [Epub ahead of print] PubMed PMID: 26228577.
Abstract: Varicocele is a frequent cause of impaired testicular function that has been associated with increased levels of sperm DNA fragmentation (SDF). Sperm with degraded DNA (DDS), as observed using the sperm chromatin dispersion (SCD) test, represent a subpopulation of spermatozoa with extensive DNA and nuclear protein damage... 
Author: Sandro C. Esteves
Abstract: Gonadotropin therapy is an essential element in infertility treatments involving assisted reproductive technology. In recent years there have been outstanding advances in the development of new gonadotropins, particularly with the production of gonadotropins using biotechnological resources. Recombinant gonadotropins have higher specific activity compared with urinary counterparts, thus allowing subcutaneous administration of minimal amounts of glycoprotein...
Authors: Fabiana Y. Nakano; Rogério de Barros F. Leão; Sandro C. Esteves
Abstract: Unexplained infertility diagnosis is made in the presence of a normal semen analysis when tubal patency and normal ovulatory function are established. Among several potential causes, unexplained infertility could be attributed to vaginal pH and cervical mucus abnormalities... 
Yours sincerely,

Sandro Esteves, MD, PhD



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